Protein Purification Reagents and Kits
Tosoh Bioscience LLC TSKGEL BUTYL-NPR 4.6X35
Column, Nonporous (NPR) HPLC; Hydrophobic Interaction; Tosoh TSKgel Butyl-NPR; Media: Nonporous polymer; Particle: 2.5 micrometer; 4.6mm I.D. x 3.5cm Length
Abcam Cyclic Pifithrin-alpha hydrobromide, pifithrin-alpha analog, 10MG
MW 349.3 Da, Purity >98%. Stable, cell-permeable analog of pifithrin-α (ab120478). Inhibits p53-mediated apoptosis and p53-dependent gene transcription. Prevents dexamethasone-induced cell death in murine thymocytes (EC₅₀ = 2.01 μM). Potent STAT6 transcriptional inhibitor. Active in vivo and in vitro. See similar compound
The product is subject to the following: Abcam Restricted Use Statement
Biotium CD45RA(111-1C5), CF594 conjugate, 0.1mg/mL
Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA (Workshop III). CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4 T-cells, 50% of peripheral CD8 T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4 or CD8 T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO positive) from B cell lymphomas (CD45RA positive).Primary antibodies are available purified, or with a selection of fluoresc
Genscript Corporation MSLN/Mesothelin298-600 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF)
Genscript Corporation CD96/TACTILEBiotin His Av
The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells and recent studies suggest both play important inhibitory roles in immune function CD96 has been shown to modulate immune cell activity in mice with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor CD226 offers unique strategies for immuno-oncology drug development
Genscript Corporation CD8 alpha/CD8ABiotin His
CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I favoring lipid raft partitioning of TCR and inducing intracellular signaling CD8 alpha is also found on dendritic cells and rat macrophages but whether CD8 alpha enhances responses of a partner receptor like TCR to activate these cells is not known
BIOHIPPO h/m EGFR-sh-RFP-BSD
h/m EGFR-sh-RFP-BSD shRNA lentiviral vector expressing RFP with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m EGFR shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse epidermal growth factor receptor (EGFR) The shRNA has been validated to meet or exceed 70% knockdown of EGFR using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Cayman Chemical NavenI PD1PD-L1 Ato647N 100RXN
A metabolite of bortezomib a degradation product of bortezomib formed under oxidative conditions
Cayman Chemical NavenIFlex TIsue MR RED 100RXN
A metabolite of isoleucine induces the formation of TBARS in isolated rat cerebral cortex at 0.5-5 mM elevated levels of are associated with 2-MBCDD also known as SBCAD